Actively Enrolling
Branch Retinal Vein Occlusion
Kodiak Sciences Inc. - KS301P103
A Prospective, Randomized, Double-masked, Active Comparator-controlled, Multi-center, Two-arm, Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal KSI-301 Compared with Intravitreal Aflibercept in Participants with Visual Impairment Due to Treatment-naïve Macular Edema Secondary to Retinal Vein Occlusion (RVO)
Genentech, Inc. - GR41984
A Phase III, Multicenter, Randomized, Double-Masked, Active Comparator-Controlled Study to Evaluate The Efficacy and Safety of Faricimab In Patients With Macular Edema Secondary To Branch Retinal Vein Occlusion
Central Retinal Vein Occlusion
Genentech, Inc. - GR41986
A Phase III, Multicenter, Randomized, Double-Masked, Active-Comparator-Controlled Study To Evaluate The Efficacy and Safety of Faricimab In Patients With Macular Edema Secondary To Central Retinal Or Hemiretinal Vein Occlusion
Diabetic Retinopathy
Genentech, Inc. - GR41675
A Phase III, Multicenter, Randomized Study of The Efficacy, Safety, and Pharmacokinatics of The Port Delivery System With Ranibizumab In Patients With Diabetic Retinopathy
Diabetic Macular Edema
Oculis – DX 221
A Phase 3, Double-Masked, Randomized, Multicenter Study of the Efficacy and Safety of OCS 01 Eye Drops in Subjects with Diabetic Macular Edema
Geographic Atrophy
Aviceda – AVD-104-C01
A Phase 2, Single and Multiple Dose Study to Evaluate Safety, Pharmacokinetics, and Treatment Effect of Intravitreal AVD-104 in Participants with Geographic Atrophy Secondary to Age-related Macular Degeneration
Intermediate Age-Related Macular Degeneration (iAMD)
Genentech – GE43220
A Multicenter, Prospective, Observational Study of the Progression of Intermediate Age-Related Macular Degeneration
Macular Telangiectasia
The Lowy Medical Research Institute – NHOR
A Natural History Observation and Registry Study of Macular Telangiectasia Type-2
Stargardts Disease
IVERIC - OPH2005
Wet AMD
Outlook Therapeutics – ONS-5010
A Phase 3, 3-Month Study to Assess the Safety and Effectiveness of ONS-5010 Compared to Lucentis in Subjects with Neovascular Age-related Macular Degeneration: NORSE EIGHT
Ocular Therapeutix – OTX-TKI-2023-AMD-301
Phase 3 Study to Evaluate the Efficacy and Safety of Intravitreal OTX-TKI (axitinib implant) in Subjects with Neovascular Age-Related Macular Degeneration: SOLEIL/SOL 1
4D Molecular Therapy – 4D-150
A Phase 1/2 Dose-Escalation and Randomized, Controlled, Masked Expansion Trial in Adults with wet AMD Undergoing Active Anti-VEGF Treatment
Contact Information
If you are interested in learning more about these clinical trials, please contact:
- Leigh Ann Spell, Clinical Research Manager
[email protected]
803-744-0144